Enfermedad de Parkinson, información, noticias, tratamientos, fármacos, investigación, terapias.

Science Daily

Information on Parkinson's disease. Learn about Parkinson's disease treatments, symptoms, new research and medication.
  1. Parkinson's disease can begin in the gut and spread to the brain via the vagus nerve, researchers report. This pathway was observed in a new mouse model, which recapitulates both motor and non-motor deficits as well as early-stage and late-stage features associated with Parkinson's disease.
  2. An international team of researchers challenges the conventional understanding of the cause of Parkinson's disease. The researchers have shown that the inclusions in the brain's neurons, characteristic of Parkinson's disease, are comprised of a membranous medley rather than protein fibrils.
  3. Researchers have discovered a secret sauce in the brain's vascular system that preserves the neurons needed to keep dementia and other diseases at bay.
  4. An enzyme that modifies chemicals formed in the body by alcohol, tobacco, and certain foods may be a new target for treating Parkinson's disease. The altered compounds, the researchers found, may play a role in triggering the onset or advancing the progression of the neurodegenerative condition.
  5. Researchers have discovered a new mechanism that brain cells use to protect themselves from protein aggregates. Such aggregates play a key role in Parkinson's and other neurodegenerative diseases.
  6. Researchers have developed a technique that could open up new ways to facilitate targeted drug delivery into the brain, enabling drugs to treat brain diseases more focally. They used transcranial, focused ultrasound and intravenously injected microbubbles into the blood-brain barrier (BBB) to make a localized, transient opening that allows drugs to cross through the BBB reversibly and noninvasively.
  7. Tiny channels between nerve cells are involved in a newly discovered mechanism of how Parkinson's disease can spread throughout the brain, according to new research from Linköping University, Sweden. The results demonstrate that harmful protein aggregates, or deposits, can bind and 'hitch a lift' with channel-forming proteins, and in this way spread to healthy cells. The study has been published in Acta Neuropathologica.
  8. People who have bipolar disorder may be more likely to later develop Parkinson's disease than people who do not have bipolar disorder, according at a new study.
  9. The relay station of the brain, the substantia nigra, consists of different types of nerve cells and is responsible for controlling the execution of diverse movements. Researchers have now characterized two of these cell populations more precisely and has been able to assign an exact function to each of them.
  10. Patients who had their appendix removed were more likely to develop Parkinson's disease than those whose appendix remained in place, according to the largest study to address the relationship between the two conditions. The retrospective study involving more than 62 million patient records from 26 health systems.

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